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Stockholders' Equity - Summary of Outstanding Warrant (Detail) (USD $)
3 Months Ended 0 Months Ended 0 Months Ended
Mar. 31, 2013
Mar. 31, 2013
October 2006
Mar. 31, 2013
June 22, 2007
Mar. 31, 2013
August 25, 2008
Mar. 31, 2013
August 3, 2009
Mar. 31, 2013
September 4, 2009
Mar. 31, 2013
April 30, 2010 through July 1, 2010
Minimum
Mar. 31, 2013
April 30, 2010 through July 1, 2010
Maximum
Mar. 31, 2013
July 22, 2010
Mar. 31, 2013
October 13, 2010 and October 19, 2010
Minimum
Mar. 31, 2013
October 13, 2010 and October 19, 2010
Maximum
Mar. 31, 2013
January 3, 2011
Mar. 31, 2013
January 12, 2011
Mar. 31, 2013
February 18, 2011
Mar. 31, 2013
February 18, 2011; Series B
Series B
Mar. 31, 2013
May 9, 2011
Mar. 31, 2013
May 20, 2011
Mar. 31, 2013
June 15, 2011, first issue
Mar. 31, 2013
June 15, 2011, second issue
Mar. 31, 2013
June 15, 2011, third issue
Mar. 31, 2013
June 20, 2011, first issue
Mar. 31, 2013
June 20, 2011, second issue
Mar. 31, 2013
July 6, 2011
Mar. 31, 2013
August 23, 2011
Mar. 31, 2013
September 29, 2011
Mar. 31, 2013
October 12, 2011
Mar. 31, 2013
October 17, 2011 through October 21, 2011
Minimum
Mar. 31, 2013
October 17, 2011 through October 21, 2011
Maximum
Mar. 31, 2013
November 2, 2011
Mar. 31, 2013
December 21, 2011
Mar. 31, 2013
January 19, 2012
Mar. 31, 2013
March 20, 2012; Series B
Series B
Mar. 31, 2013
March 21, 2012; Series B
Series B
Mar. 31, 2013
May 3,2012; Series B
Series B
Mar. 31, 2013
June 4, 2012; Series B
Series B
Mar. 31, 2013
May 8, 2012
Maximum
Mar. 31, 2013
May 7, 2012
Minimum
Mar. 31, 2013
May 7, 2012
Maximum
Mar. 31, 2013
June 22, 2012
Mar. 31, 2013
June 28, 2012
Mar. 31, 2013
July 25, 2012
Mar. 31, 2013
January 2013
Jan. 24, 2013
January 2013 Bridge Notes
May 15, 2013
Subsequent Event
October 2006
Mar. 31, 2013
Subsequent Event
October 2006
Jan. 24, 2013
Subsequent Event
January 2013 Bridge Notes
Jan. 24, 2013
Subsequent Event
January 2013 Bridge Notes
Maximum
Warranty Liability [Line Items]                                                                                              
Percentage of Purchase Price Each Warrant Entitle Investor to Purchase                                                                                     100.00%        
Expiration Date   Apr. 27, 2014 [1] Dec. 22, 2014 [2] Aug. 25, 2015 [3] Aug. 03, 2014 [2] Sep. 04, 2014 [2] Apr. 30, 2015 Jul. 01, 2015 Jul. 22, 2013 [2] Oct. 13, 2015 Oct. 19, 2015 Feb. 18, 2014 [2] Jan. 12, 2014 [2] Feb. 18, 2016 [2] Feb. 18, 2016 [2] May 08, 2014 [2] May 19, 2014 [2] Jun. 15, 2016 [2] Jun. 15, 2018 [2] Jun. 15, 2018 [2] Jun. 20, 2016 [2] Jun. 20, 2018 [2] Jul. 06, 2016 [2] Aug. 23, 2016 [2] Sep. 29, 2016 [3] Oct. 12, 2016 [3] Oct. 17, 2016 Oct. 21, 2016 Nov. 02, 2014 [2] Dec. 21, 2016 [2] Jan. 19, 2017 [2] Mar. 20, 2017 [2] Mar. 21, 2017 [2] May 03, 2017 [2] Jun. 04, 2017 [2] May 07, 2013 [2] May 07, 2019 [2] May 08, 2019 [2] Jun. 22, 2017 [2] Jun. 28, 2017 [2] Jul. 25, 2017 [2] Jul. 25, 2018 [4]          
Shares Subject to Outstanding Warrants $ 41,032,048 $ 4,563,640 $ 257,583 $ 1,398,964 $ 32,005 $ 83,476 $ 222,217   $ 96,859 $ 36,197   $ 277,777 $ 131,892 $ 759,370 $ 393,933 $ 78,455 $ 90,313 $ 1,445,862 $ 45,000 $ 120,271 $ 57,079 $ 132 $ 419,729 $ 115,000 $ 550,703 $ 564,348 $ 76,555   $ 540,000 $ 6,315,789 $ 132,750 $ 5,244,000 $ 6,624,000 $ 110,450 $ 204,450 $ 917,839 $ 555,556 $ 200,000 $ 4,029,851 $ 719,178 $ 2,075,825 $ 1,545,000   $ 5,602,879 $ 4,563,639    
Exercise Price at End of Period 3.90 0.62 41.80 38.60 17.00 17.00 18.20   18.20 13.40   9.00 9.20 6.57 6.00 2.92 2.92 3.85 3.12 3.85     3.85 3.85 0.83 0.83 2.64   2.12 1.22 1.22 1.02 1.02 1.02 1.02 2.12 0.90 0.90 0.85 0.85 0.89 1.00   0.51 0.62    
Unit Purchase Price Each Warrant Entitle Investor to Purchase                                                                                     $ 1.00     $ 1.00  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                                                                                     1,500,000        
Class of Warrant or Right, Term                                                                                     5 years 6 months        
Class of Warrant or Right, Floor Price                                                                                     $ 0.71        
Class of Warrant or Right, Price Above Consolidated Closing Bid Price to Adjust Initial Exercise Price for Additional Warrants                                                                                           $ 0.01  
Class of Warrant or Right, Number of Securities Underlying Additional Warrants                                                                                     500,000       500,000
Class of Warrant or Right, Price Above Consolidated Closing Bid Price to Adjust Exercise Price                                                                                           $ 0.01  
Class of Warrant or Right, Amount of Common Stock to Purchase of Warrant Issued to Private Placement Agent                                                                                           45,000  
[1] Yes; contract provides for reset of exercise price along with increase in number of shares in connection with sales of future equity below current exercise price
[2] No; contract does not provide for an exercise price reset provision.
[3] Yes; contract provides for a price reset provision; however, provision is no longer applicable.
[4] Yes; contract provides for reset of exercise price under certain conditions, subject to a floor of $0.71; contract also provides for the issuance of additional warrants to purchase up to 500,000 shares of common stock if the remaining principal on the January 2013 Bridge Notes is not paid in full on or before July 1, 2013.