CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $)	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Revenue:
Net product sales	$ 3,505,095	$ 3,545,741
Contract revenue	902,162	2,359,563
Total revenue	4,407,257	5,905,304
Costs and expenses:
Cost of product sales	2,603,876	2,506,879
Research and development	2,354,500	3,941,269
Selling, general and administrative	3,328,607	3,492,491
Total operating costs and expenses	8,286,983	9,940,639
Operating loss	(3,879,726)	(4,035,335)
Interest expense, net	(1,395,433)	(3,245,227)
Fair value adjustments of derivative instruments, net	87,000	106,000
Loss on settlement of debt and derivative instruments, net	0	(95,450)
Equity in losses of affiliates, net	(5,998)	(121,590)
Loss from continuing operations before income taxes	(5,194,157)	(7,391,602)
Income tax expense	(1,600)	0
Loss from continuing operations	(5,195,757)	(7,391,602)
Loss from discontinued operations, net of taxes	(1,708,163)	(423,288)
Net loss attributable to stockholders	(6,903,920)	(7,814,890)
Per share data-basic and diluted:
Loss from continuing operations	$ (0.11)	$ (0.25)
Loss from discontinued operations	$ (0.03)	$ (0.01)
Net loss attributable to stockholders	$ (0.14)	$ (0.26)
Weighted average shares outstanding:
Basic and diluted	48,356,602	29,503,356
Comprehensive loss:
Net loss attributable to stockholders	(6,903,920)	(7,814,890)
Foreign currency translation adjustments, net of tax	(155,791)	51,944
Comprehensive loss attributable to stockholders	$ (7,059,711)	$ (7,762,946)