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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 K+aMqTt/h6/M4m8totgnfCYI9/58QJwd/PKDYsxsn9V2bMnGK+2N4+BfY/8ckwpw
 6oGAg27TRd7iF3r4mNPsWg==

<SEC-DOCUMENT>0001206774-08-001220.txt : 20080630
<SEC-HEADER>0001206774-08-001220.hdr.sgml : 20080630
<ACCEPTANCE-DATETIME>20080630162502
ACCESSION NUMBER:		0001206774-08-001220
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080630
FILED AS OF DATE:		20080630
DATE AS OF CHANGE:		20080630

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LYRIS, INC.
		CENTRAL INDEX KEY:			0001166220
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-PREPACKAGED SOFTWARE [7372]
		IRS NUMBER:				010579490
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		103 FOULK ROAD
		STREET 2:		SUITE 205Q
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19803
		BUSINESS PHONE:		302 691-6189

	MAIL ADDRESS:	
		STREET 1:		103 FOULK ROAD
		STREET 2:		SUITE 205Q
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19803

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JL HALSEY CORP
		DATE OF NAME CHANGE:	20020129

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Polanco Raymond
		CENTRAL INDEX KEY:			0001438497

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	333-82154
		FILM NUMBER:		08926140

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		408-844-2989

	MAIL ADDRESS:	
		STREET 1:		368 RIESLING CT.
		CITY:			FREMONT
		STATE:			CA
		ZIP:			94539
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>lyris_form3ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2008-06-30</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001166220</issuerCik>
        <issuerName>LYRIS, INC.</issuerName>
        <issuerTradingSymbol>LYRI.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001438497</rptOwnerCik>
            <rptOwnerName>Polanco Raymond</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O LYRIS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>103 FOULK ROAD, SUITE 205Q</rptOwnerStreet2>
            <rptOwnerCity>WILMINGTON</rptOwnerCity>
            <rptOwnerState>DE</rptOwnerState>
            <rptOwnerZipCode>19803</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>VP of Client Services</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.91</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2017-05-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.89</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-02-19</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>100000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This option was granted on June 6, 2007 and is exercisable in four equal annual installments beginning May 1, 2008. The first
 installment aggregating 2,625 shares is exercisable currently. The next three installments become exercisable on May 1,
 2009, May 1, 2010 and May 1, 2011, respectively.</footnote>
        <footnote id="F2">This option was granted on February 19, 2008 and is exercisable in four equal annual installments beginning February 19,
 2009.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/S/ Raymond Polanco</signatureName>
        <signatureDate>2008-06-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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