-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 RuHJSHFJbg1XDXdH+OOf9UmziN+gwD3zJYU33YCXEDsWXLeEyod0rvef7UBqAZyc
 jROCimkDsBfOdRIulzvyKw==

<SEC-DOCUMENT>0001206774-08-001041.txt : 20080516
<SEC-HEADER>0001206774-08-001041.hdr.sgml : 20080516
<ACCEPTANCE-DATETIME>20080516164419
ACCESSION NUMBER:		0001206774-08-001041
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080509
FILED AS OF DATE:		20080516
DATE AS OF CHANGE:		20080516

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LYRIS, INC.
		CENTRAL INDEX KEY:			0001166220
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-PREPACKAGED SOFTWARE [7372]
		IRS NUMBER:				010579490
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		103 FOULK ROAD
		STREET 2:		SUITE 205Q
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19803
		BUSINESS PHONE:		302 691-6189

	MAIL ADDRESS:	
		STREET 1:		103 FOULK ROAD
		STREET 2:		SUITE 205Q
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19803

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JL HALSEY CORP
		DATE OF NAME CHANGE:	20020129

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Mackintosh Heidi L
		CENTRAL INDEX KEY:			0001434400

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	333-82154
		FILM NUMBER:		08842884

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		510-844-1600

	MAIL ADDRESS:	
		STREET 1:		129 PARAISO DR.
		CITY:			DANVILLE
		STATE:			CA
		ZIP:			94526
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>mackintosh_form4ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2008-05-09</periodOfReport>

    <dateOfOriginalSubmission>2008-05-14</dateOfOriginalSubmission>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001166220</issuerCik>
        <issuerName>LYRIS, INC.</issuerName>
        <issuerTradingSymbol>LYRI.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001434400</rptOwnerCik>
            <rptOwnerName>Mackintosh Heidi L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O LYRIS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>103 FOULK RD., SUITE 205Q</rptOwnerStreet2>
            <rptOwnerCity>WILMINGTON</rptOwnerCity>
            <rptOwnerState>DE</rptOwnerState>
            <rptOwnerZipCode>19803</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Financial Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Employee Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.83</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-05-09</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>400000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-05-09</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>400000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>400000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The Option vests and becomes exercisable in cumulative installments as follows: (i) the Option shall become exercisable with
 respect to twenty five percent (25%) of the Option shares on May 9, 2009; and (ii) the option shall be exercisable with
 respect to the remaining seventy five percent (75%) in equal quarterly installments through May 9, 2012.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Heidi L. Mackintosh</signatureName>
        <signatureDate>2008-05-14</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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