<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2012-10-01</periodOfReport>

    <dateOfOriginalSubmission>2012-10-01</dateOfOriginalSubmission>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001166036</issuerCik>
        <issuerName>MARKWEST ENERGY PARTNERS L P</issuerName>
        <issuerTradingSymbol>MWE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001235082</rptOwnerCik>
            <rptOwnerName>MOLLENKOPF JOHN C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O MARKWEST ENERGY PARTNERS, L.P.</rptOwnerStreet1>
            <rptOwnerStreet2>1515 ARAPAHOE ST. TWR 1, STE 1600</rptOwnerStreet2>
            <rptOwnerCity>DENVER</rptOwnerCity>
            <rptOwnerState>CO</rptOwnerState>
            <rptOwnerZipCode>80202</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>SVP, Chief Operating Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Units</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>311870</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">On October 1, 2012, the reporting person mistakenly filed a Form 4 reporting a sale of 10,000 common units that did not in fact occur, due to a broker error.  As of October 1, 2012, the reporting person owned 311,870 units.</footnote>
        <footnote id="F2">Amount of securities beneficially owned following the reported transaction(s) includes Common Units owned and Restricted Units subject to varying vesting terms.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Sean M. McKendry as POA for John Mollenkopf</signatureName>
        <signatureDate>2012-10-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
