Gary R. Henrie

Attorney at Law

Licensed in Nevada

315 Kimball’s Garden Circle Telephone: 309-313-5092

Nauvoo, IL 62354 e-mail: grhlaw@hotmail.com

October 25, 2018

GB Sciences, Inc.

3550 W. Teco Avenue

Las Vegas, Nevada 89118

Re: GB Sciences, Inc., Registration Statement on Form S-8

Ladies and Gentlemen:

I have acted as securities counsel for GB Sciences, Inc., a Nevada corporation (the "Company"), for the purpose of issuing this opinion letter in connection with the registration statement on Form S-8 (the "Registration Statement") to be filed with the Securities and Exchange Commission pursuant to the Securities Act of 1933, as amended. The Registration Statement relates to the offering of 10,000,000 shares of the Company’s common stock by the Company pursuant to an employee benefit plan.

In rendering the opinion set forth below, I have reviewed: (a) the Registration Statement; (b) the Company's Articles of Incorporation; (c) the Company's Bylaws; (d) relevant employee benefit plans; and (e) such statutes, records and other documents as I have deemed relevant. In my examination, I have assumed the genuineness of all signatures, the authenticity of all documents submitted to me as originals, and conformity with the originals of all documents submitted to me as copies thereof and the truthfulness of statements set forth in such documents. In addition, I have made such other examinations of law and fact, as I have deemed relevant in order to form a basis for the opinions hereinafter expressed.

Based upon the foregoing, I am of the opinion that the 10,000,000 shares of common stock to be issued by the Company pursuant to the employee benefit plan, will be validly issued, fully paid and nonassessable. This opinion is based on Nevada general corporate law, all applicable Nevada statutory provisions and reported judicial decisions interpreting these laws.

Very truly yours,

/s/ Gary R. Henrie

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Gary R. Henrie, Esq.