X0306 4 2018-05-23 0000922247 CTD HOLDINGS INC CTDH 0001163556 FINE N SCOTT 6714 NW 16TH STREET, SUITE B GAINESVILLE FL 32163 1 1 Chief Executive Officer Common Stock 2018-05-23 4 C 0 800000 A 6045714 D Series B Convertible Preferred Stock 0.25 2018-05-23 4 C 0 2000 D Common Stock 800000 0 D Reflects the automatic conversion of Series B Convertible Preferred Stock ("Series B Preferred") into Common Stock upon the filing of Articles of Amendment to the Issuer's Articles of Incorporation increasing the Issuer's authorized shares of Common Stock. The conversion is an exempt transaction pursuant to Rule 16b-7 under the Securities Exchange Act of 1934, as amended. The Series B Preferred were included in "Units" purchased by the reporting person for $100 per Unit. Each Unit consisted of one share of Series B Preferred convertible into 400 shares of Common Stock and one warrant to purchase 400 shares of Common Stock. Reflects the conversion of 1,000 shares of Series B Preferred held by the pension plan of a limited liability company of which the reporting person is the sole member, into 400,000 shares of Common Stock. /s/ N. Scott Fine 2018-06-28