X0306 4 2014-11-18 0 0000926617 VERMILLION, INC. VRML 0001162956 LAFRANCE JAMES T 12117 BEE CAVES RD BUILDING THREE, SUITE 100 AUSTIN TX 78738 1 1 0 0 President & Chief Exec Officer Common Stock 2014-11-18 4 P 0 29940 1.4 A 38440 D Common Stock 2014-11-19 4 P 0 11675 1.5 A 50115 D The purchase reported in column 4 is a weighted average price. The shares were purchased in multiple transactions ranging from $1.26 to $1.50. The reporting person undertakes to provide to Vermillion, any security holder of Vermillion or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote. The purchase reported in column 4 is a weighted average price. The shares were purchased in multiple transactions ranging from $1.44 to $1.51. The reporting person undertakes to provide to Vermillion, any security holder of Vermillion or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote. /s/ James LaFrance 2014-11-20