Balance Sheet Details - Property and Equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Property and equipment	$ 50,188	$ 31,544
Less accumulated depreciation and amortization	(26,703)	(23,989)
Construction-in-progress	4,549	9,976
Property and equipment, net	28,034	17,531
Computer equipment and software
Property, Plant and Equipment [Line Items]
Property and equipment	5,759	4,240
Laboratory and manufacturing equipment
Property, Plant and Equipment [Line Items]
Property and equipment	30,260	18,107
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property and equipment	12,095	7,203
Office, furniture and fixtures
Property, Plant and Equipment [Line Items]
Property and equipment	$ 2,074	$ 1,994

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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