X0306 4 2015-03-24 1 0001157602 Vitae Pharmaceuticals, Inc VTAE 0001162057 PROSPECT MANAGEMENT CO II LLC C/O PROSPECT VENTURE PARTNERS 435 TASSO STREET, SUITE 200 PALO ALTO CA 94301 0 0 1 0 0001135669 PROSPECT VENTURE PARTNERS II LP C/O PROSPECT VENTURE PARTNERS 435 TASSO STREET, SUITE 200 PALO ALTO CA 94301 0 0 1 0 0001162055 PROSPECT VENTURE PARTNERS LP C/O PROSPECT VENTURE PARTNERS 435 TASSO STREET, SUITE 200 PALO ALTO CA 94301 0 0 1 0 0001162056 PROSPECT MANAGEMENT CO LLC C/O PROSPECT VENTURE PARTNERS 435 TASSO STREET, SUITE 200 PALO ALTO CA 94301 0 0 1 0 0001162059 HIRSCH RUSSELL C C/O PROSPECT VENTURE PARTNERS 435 TASSO STREET, SUITE 200 PALO ALTO CA 94301 0 0 1 0 0001162060 SCHNELL DAVID C/O PROSPECT VENTURE PARTNERS 435 TASSO STREET, SUITE 200 PALO ALTO CA 94301 0 0 1 0 Common Stock 2015-03-24 4 J 0 900383 0 D 1672140 I See Footnote Common Stock 2015-03-24 4 J 0 20357 0 A 32584 I See Footnote Common Stock 2015-03-24 4 J 0 20357 0 A 28237 I See Footnote Common Stock 395799 I See Footnote Common Stock 0 I See Footnote Common Stock 0 I See Footnote Represents a pro rata distribution without additional consideration by Prospect Venture Partners II, L.P. ("PVP II"). The reportable securities are owned by PVP II. Prospect Management Co. II, L.L.C. ("PMC II") is the general partner of PVP II. Russell Hirsch ("Hirsch") and David Schnell ("Schnell") are the managing members of PMC II. Each of PMC II, Hirsch and Schnell disclaim beneficial ownership of these securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of its pecuniary interest therein. Acquisition by The Hirsch Living Trust Dated 9/22/2000 ("Hirsch Trust") pursuant to a pro rata distribution without additional consideration by PVP II. Includes 4,347 shares previously held through Prospect Venture Partner, L.P. ("PVP"), as Nominee and 7,880 shares previously held through PVP II, as Nominee that are now held directly by Hirsch Trust. The reportable securities are owned directly by Hirsch Trust. Hirsch is a trustee of Hirsch Trust. Acquisition by David Schnell, Trust 2000 U/L DTD May 26, 2000 ("Schnell Trust") pursuant to a pro rata distribution without additional consideration by PVP II. Includes 7,880 shares previously held through PVP II, as Nominee that are now held directly by Schnell Trust. The reportable securities are owned directly by Schnell Trust. Schnell is a trustee of Schnell Trust. The reportable securities are owned by PVP. Prospect Management Co., L.L.C. ("PMC") is the general partner of PVP. Schnell is the managing member of PMC. Each of PMC and Schnell disclaim beneficial ownership of these securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of its pecuniary interest therein. The shares previously reported as held by PVP, as Nominee are now being held directly in each of the Beneficial Owners' names. The reportable securities are owned by PVP, as Nominee. PMC is the general partner of PVP. Schnell is the managing member of PMC. Each of PMC and Schnell disclaim beneficial ownership of these securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of its pecuniary interest therein. The shares previously reported as held by PVP II, as Nominee are now being held directly in each of the Beneficial Owners' names. The reportable securities are owned by PVP II, as Nominee. PMC II is the general partner of PVP II. Hirsch and Schnell are the managing members of PMC II. Each of PMC II, Hirsch and Schnell disclaim beneficial ownership of these securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of its pecuniary interest therein. /s/ David Schnell, Managing Member Prospect Management Company, L.L.C., the General Partner of Prospect Venture Partners, L.P. 2015-03-26 /s/ David Schnell, Managing Member Prospect Management Company, L.L.C. 2015-03-26 /s/ David Schnell, Managing Member Prospect Management Company II, L.L.C., the General Partner of Prospect Venture Partners II, L.P. 2015-03-26 /s/ David Schnell, Managing Member Prospect Management Company II, L.L.C. 2015-03-26 /s/ Russell Hirsch 2015-03-26 /s/ David Schnell 2015-03-26