X0202 3 2004-12-01 0 0001161924 ADVANCIS PHARMACEUTICAL CORP AVNC 0001311080 Clausen Susan P 20425 SENECA MEADOWS PARKWAY GERMANTOWN MD 20876 0 1 0 0 Vice President Stock Option (Right to Buy) 0.77 2013-09-01 Common Stock 50000 D Stock Option (Right to Buy) 8.40 2014-09-15 Common Stock 30000 D 25% of the Options vest and become exercisable each year, commencing one year after September 8, 2003 (the "Initial Vesting Date") and on such day of every year thereafter, through the fourth anniversary of the Initial Vesting Date. 2.083% of the Options vest and become exercisable each month, commencing one month after August 15, 2004 (the "Initial Investing Date") and on such day of every month thereafter, through the fourth anniversary of the Initial Vesting Date. Exhibit List Exhibit 24 - Power of Attorney dated December 8, 2004 /s/ Steven A. Shallcross, attorney-in-fact 2004-12-09