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Goodwill and IPR&D - Summary of Goodwill and IPR&D (Detail) - USD ($)
$ in Thousands
Dec. 31, 2015
Dec. 31, 2014
Feb. 27, 2014
Goodwill And Intangible Assets [Line Items]      
Goodwill $ 3,007 $ 3,007  
In-process research and development     $ 2,000
Total goodwill and IPR&D 11,556    
SynthRx [Member]      
Goodwill And Intangible Assets [Line Items]      
In-process research and development 6,549    
Aires [Member]      
Goodwill And Intangible Assets [Line Items]      
In-process research and development $ 2,000