Consolidated Statements of Operations and Comprehensive Loss - USD ($)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
Income Statement [Abstract]
Revenues	$ 0	$ 0
Operating expenses:
Research and development	28,264,000	19,435,000
Selling, general and administrative	10,963,000	9,488,000
Transaction-related expenses		271,000
Depreciation and amortization	146,000	85,000
Total operating expenses	39,373,000	29,279,000
Loss from operations	(39,373,000)	(29,279,000)
Interest income	130,000	69,000
Interest expense	(603,000)
Other income, net	4,000	508,000
Net loss	$ (39,842,000)	$ (28,702,000)
Net loss per share - basic and diluted	$ (0.25)	$ (0.23)
Weighted average shares outstanding - basic and diluted	162,219,116	122,409,183
Comprehensive Loss:
Net loss	$ (39,842,000)	$ (28,702,000)
Other comprehensive income/(loss)	8,000	(4,000)
Comprehensive loss	$ (39,834,000)	$ (28,706,000)