Shareholders' Equity (Tables)

6 Months Ended

Jun. 30, 2022

Equity [Abstract]

Summary of Net Proceeds after Deducting Underwriting Discounts Commissions and Offering Expenses

The Public Offering resulted in net proceeds to the Company of approximately $122.2 million, after deducting final underwriting discounts, commissions and offering expenses, as follows (in thousands):

Financial instruments	Proceeds
Common stock	$	83,346
2021 Pre-funded Warrants		46,622
Total		129,968
Offering expenses		(7,737	)
Net proceeds	$	122,231

Company's Shares of Common Stock Reserved for Issuance

The Company’s shares of common stock reserved for issuance as of the periods indicated were as follows:

	June 30, 2022		December 31, 2021
April 2017 Warrants		24,725		24,725
June 2017 Warrants		41,736		41,736
December 2018 Warrants		11,332		11,332
2017 Pre-funded Warrants		775,000		775,000
Pre-funded PIPE Warrants		5,780,537		5,780,537
2021 Pre-funded Warrants		32,175,172		32,175,172
Stock options outstanding		6,064,278		6,218,841
Issued and nonvested RSUs		1,141,875		1,272,375
Total shares reserved		46,014,655		46,299,718

Summary of Outstanding Warrants for Company's Common Stock

The following table summarizes the outstanding warrants for the Company’s common stock as of June 30, 2022:

Expiration Date	Shares Underlying Outstanding Warrants		Exercise Price
October 2024		775,000	$	0.01
April 2027		24,725	$	2.87
June 2027		41,736	$	2.87
December 2028		11,332	$	2.87
None		37,955,709	$	0.001
		38,808,502

Components of Accumulated Other Comprehensive Income (Loss)

The components of accumulated other comprehensive income (loss) as of the dates indicated and the change during the period were (in thousands):

	Foreign Exchange Translation Adjustment			Unrealized Gain (Loss) on ST Investments			Total Accumulated Other Comprehensive Income (Loss)
Balance, December 31, 2020	$	941		$	1		$	942
Change		(887	)		(50	)		(937	)
Balance, December 31, 2021		54		$	(49	)		5
Change		(953	)		(68	)		(1,021	)
Balance, June 30, 2022	$	(899	)	$	(117	)	$	(1,016	)