X0306 4 2020-04-30 0 0001159036 HALOZYME THERAPEUTICS, INC. HALO 0001630914 BIZZARI JEAN-PIERRE C/O HALOZYME THERAPEUTICS, INC. 11388 SORRENTO VALLEY ROAD SAN DIEGO CA 92121 1 0 0 0 Common Stock 2020-04-30 4 A 0 8829 0 A 82314 D Represents annual restricted stock grant under the Issuer's director compensation program. This grant will vest in full on the earlier of (i) April 30, 2021 and (ii) the date of the Issuer's next annual meeting of stockholders. /s/ James R. Oehler as attorney-in-fact for Jean-Pierre Bizzari 2020-05-01