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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
Nonrelated Party
Related Party
Preferred stock
Common stock
Common stock
Nonrelated Party
Common stock
Related Party
Additional paid-in Capital
Additional paid-in Capital
Nonrelated Party
Additional paid-in Capital
Related Party
Accumulated other comprehensive income (loss)
Accumulated deficit
Balance (in shares) at Dec. 31, 2023       2,369,797 19,875,427              
Balance at Dec. 31, 2023 $ 405,333     $ 0 $ 2     $ 1,741,153     $ 468 $ (1,336,290)
Increase (Decrease) in Stockholders' Equity                        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)           750,000            
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs   $ 311,560             $ 311,560      
Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs (in shares)             59,236          
Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs     $ 262,145             $ 262,145    
Stock-based compensation expense related to equity-classified awards 19,902             19,902        
Unrealized loss on marketable securities and foreign currency (640)                   (640)  
Net loss (147,541)                     (147,541)
Balance (in shares) at Mar. 31, 2024       2,369,797 20,684,663              
Balance at Mar. 31, 2024 850,759     $ 0 $ 2     2,334,760     (172) (1,483,831)
Balance (in shares) at Dec. 31, 2023       2,369,797 19,875,427              
Balance at Dec. 31, 2023 405,333     $ 0 $ 2     1,741,153     468 (1,336,290)
Increase (Decrease) in Stockholders' Equity                        
Net loss (299,512)                      
Balance (in shares) at Jun. 30, 2024       2,369,797 21,700,893              
Balance at Jun. 30, 2024 857,120     $ 0 $ 2     2,493,288     (368) (1,635,802)
Balance (in shares) at Mar. 31, 2024       2,369,797 20,684,663              
Balance at Mar. 31, 2024 850,759     $ 0 $ 2     2,334,760     (172) (1,483,831)
Increase (Decrease) in Stockholders' Equity                        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)           346,153            
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs   $ 85,950             $ 85,950      
Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs (in shares)             670,077          
Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs     $ 48,174             $ 48,174    
Stock-based compensation expense related to equity-classified awards 24,404             24,404        
Unrealized loss on marketable securities and foreign currency (196)                   (196)  
Net loss (151,971)                     (151,971)
Balance (in shares) at Jun. 30, 2024       2,369,797 21,700,893              
Balance at Jun. 30, 2024 $ 857,120     $ 0 $ 2     2,493,288     (368) (1,635,802)
Balance (in shares) at Dec. 31, 2024 22,004,679     2,369,797 22,004,679              
Balance at Dec. 31, 2024 $ 754,383     $ 0 $ 2     2,556,095     468 (1,802,182)
Increase (Decrease) in Stockholders' Equity                        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)         183,037              
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs 8,640             8,640        
Stock-based compensation expense related to equity-classified awards 20,931             20,931        
Unrealized loss on marketable securities and foreign currency (79)                   (79)  
Net loss (73,238)                     (73,238)
Balance (in shares) at Mar. 31, 2025       2,369,797 22,187,716              
Balance at Mar. 31, 2025 $ 710,637     $ 0 $ 2     2,585,666     389 (1,875,420)
Balance (in shares) at Dec. 31, 2024 22,004,679     2,369,797 22,004,679              
Balance at Dec. 31, 2024 $ 754,383     $ 0 $ 2     2,556,095     468 (1,802,182)
Increase (Decrease) in Stockholders' Equity                        
Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs (in shares) 118,658                      
Net loss $ (115,519)                      
Balance (in shares) at Jun. 30, 2025 22,221,116     2,369,797 22,221,116              
Balance at Jun. 30, 2025 $ 695,978     $ 0 $ 2     2,612,566     1,111 (1,917,701)
Balance (in shares) at Mar. 31, 2025       2,369,797 22,187,716              
Balance at Mar. 31, 2025 710,637     $ 0 $ 2     2,585,666     389 (1,875,420)
Increase (Decrease) in Stockholders' Equity                        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)         33,400              
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs 1,741             1,741        
Stock-based compensation expense related to equity-classified awards 25,159             25,159        
Unrealized loss on marketable securities and foreign currency 722                   722  
Net loss $ (42,281)                     (42,281)
Balance (in shares) at Jun. 30, 2025 22,221,116     2,369,797 22,221,116              
Balance at Jun. 30, 2025 $ 695,978     $ 0 $ 2     $ 2,612,566     $ 1,111 $ (1,917,701)