Income Taxes - Effective Income Tax Rate (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Income Tax Disclosure [Abstract]
Tax benefit at U.S. federal statutory rate	$ (97,837)	$ (78,462)	$ (62,023)
Stock based compensation	(9,954)	(8,287)	(7,844)
162M limitation	21,627	3,183	7,996
Other nondeductible expenses	835	53	16
State income taxes benefit before valuation allowance, net of federal benefit	(19,280)	(16,246)	13,090
Increase in domestic valuation allowance	125,689	112,606	59,466
Research and development credit	(17,679)	(12,971)	(10,712)
Other adjustments	(3,401)	124	11
Income tax expense (benefit)	$ 0	$ 0	$ 0