Accrued Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Accrued Liabilities, Current [Abstract]
Contract research organization costs	$ 30,250	$ 50,737
Other clinical study related costs	2,161	3,724
Manufacturing and drug supply	9,941	9,705
Compensation and benefits	34,957	17,030
Professional fees	17,512	6,814
Gross to net accrued liabilities	21,703	0
Other	8,171	1,970
Total accrued liabilities	$ 124,695	$ 89,980