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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
Related Party
Preferred stock
Common stock
Common stock
Related Party
Additional paid-in Capital
Additional paid-in Capital
Related Party
Accumulated other comprehensive income (loss)
Accumulated deficit
Balance (in shares) at Dec. 31, 2022     2,369,797 18,102,523          
Balance at Dec. 31, 2022 $ 197,389   $ 0 $ 2   $ 1,160,079   $ (32) $ (962,660)
Increase (Decrease) in Stockholders' Equity                  
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)         180,551        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs   $ 17,903         $ 17,903    
Stock-based compensation expense related to equity-classified awards and Compensation expense related to stock options for services 11,250         11,250      
Unrealized (loss) gain on marketable securities (54)             (54)  
Hercules warrant 544         544      
Net loss (76,896)               (76,896)
Balance (in shares) at Mar. 31, 2023     2,369,797 18,283,074          
Balance at Mar. 31, 2023 150,136   $ 0 $ 2   1,189,776   (86) (1,039,556)
Balance (in shares) at Dec. 31, 2022     2,369,797 18,102,523          
Balance at Dec. 31, 2022 197,389   $ 0 $ 2   1,160,079   (32) (962,660)
Increase (Decrease) in Stockholders' Equity                  
Unrealized (loss) gain on marketable securities (10)                
Net loss (261,436)                
Balance (in shares) at Sep. 30, 2023     2,369,797 18,494,192          
Balance at Sep. 30, 2023 22,249   $ 0 $ 2   1,246,385   (42) (1,224,096)
Balance (in shares) at Mar. 31, 2023     2,369,797 18,283,074          
Balance at Mar. 31, 2023 150,136   $ 0 $ 2   1,189,776   (86) (1,039,556)
Increase (Decrease) in Stockholders' Equity                  
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)       85,901 90,058        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs 21,754 6,251       21,754 6,251    
Stock-based compensation expense related to equity-classified awards and Compensation expense related to stock options for services 10,973         10,973      
Unrealized (loss) gain on marketable securities (3)             (3)  
Hercules warrant 195         195      
Net loss (85,800)               (85,800)
Balance (in shares) at Jun. 30, 2023     2,369,797 18,459,033          
Balance at Jun. 30, 2023 103,506   $ 0 $ 2   1,228,949   (89) (1,125,356)
Increase (Decrease) in Stockholders' Equity                  
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)       12,200 22,959        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs 2,731 1,924       2,731 1,924    
Stock-based compensation expense related to equity-classified awards and Compensation expense related to stock options for services 12,660         12,660      
Unrealized (loss) gain on marketable securities 47             47  
Hercules warrant 121         121      
Net loss (98,740)               (98,740)
Balance (in shares) at Sep. 30, 2023     2,369,797 18,494,192          
Balance at Sep. 30, 2023 $ 22,249   $ 0 $ 2   1,246,385   (42) (1,224,096)
Balance (in shares) at Dec. 31, 2023 19,875,427   2,369,797 19,875,427          
Balance at Dec. 31, 2023 $ 405,333   $ 0 $ 2   1,741,153   468 (1,336,290)
Increase (Decrease) in Stockholders' Equity                  
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)       750,000 59,236        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs 311,560 262,145       311,560 262,145    
Stock-based compensation expense related to equity-classified awards and Compensation expense related to stock options for services 19,902         19,902      
Unrealized (loss) gain on marketable securities (640)             (640)  
Net loss (147,541)               (147,541)
Balance (in shares) at Mar. 31, 2024     2,369,797 20,684,663          
Balance at Mar. 31, 2024 $ 850,759   $ 0 $ 2   2,334,760   (172) (1,483,831)
Balance (in shares) at Dec. 31, 2023 19,875,427   2,369,797 19,875,427          
Balance at Dec. 31, 2023 $ 405,333   $ 0 $ 2   1,741,153   468 (1,336,290)
Increase (Decrease) in Stockholders' Equity                  
Unrealized (loss) gain on marketable securities 803                
Net loss $ (406,476)                
Balance (in shares) at Sep. 30, 2024 21,806,436   2,369,797 21,806,436          
Balance at Sep. 30, 2024 $ 777,155   $ 0 $ 2   2,518,648   1,271 (1,742,766)
Balance (in shares) at Mar. 31, 2024     2,369,797 20,684,663          
Balance at Mar. 31, 2024 850,759   $ 0 $ 2   2,334,760   (172) (1,483,831)
Increase (Decrease) in Stockholders' Equity                  
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)       346,153 670,077        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs 85,950 48,174       85,950 48,174    
Stock-based compensation expense related to equity-classified awards and Compensation expense related to stock options for services 24,404         24,404      
Unrealized (loss) gain on marketable securities (196)             (196)  
Net loss (151,971)               (151,971)
Balance (in shares) at Jun. 30, 2024     2,369,797 21,700,893          
Balance at Jun. 30, 2024 857,120   $ 0 $ 2   2,493,288   (368) (1,635,802)
Increase (Decrease) in Stockholders' Equity                  
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares)         105,543        
Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs   $ 7,462         $ 7,462    
Stock-based compensation expense related to equity-classified awards and Compensation expense related to stock options for services 17,898         17,898      
Unrealized (loss) gain on marketable securities 1,639             1,639  
Net loss $ (106,964)               (106,964)
Balance (in shares) at Sep. 30, 2024 21,806,436   2,369,797 21,806,436          
Balance at Sep. 30, 2024 $ 777,155   $ 0 $ 2   $ 2,518,648   $ 1,271 $ (1,742,766)