Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Nonrelated Party	Related Party	Preferred stock	Preferred stock Nonrelated Party	Common stock	Common stock Nonrelated Party	Common stock Related Party	Additional paid-in Capital	Additional paid-in Capital Nonrelated Party	Additional paid-in Capital Related Party	Accumulated other comprehensive income (loss)	Accumulated deficit
Beginning balance (in shares) at Dec. 31, 2020				1,969,797		15,508,146
Beginning balance at Dec. 31, 2020	$ 239,970			$ 0		$ 2			$ 665,385			$ 47	$ (425,464)
Increase (Decrease) in Stockholders' Equity
Issuance of common and preferred shares in equity offerings, excluding to related parties, net of transaction costs (in shares)							1,584,169
Issuance of common shares in equity offering, excluding to related parties, net of transaction costs		$ 170,207								$ 170,207
Sale of common shares to related parties and exercise of common stock options, net of transaction costs ( in shares)								11,080
Sale of common shares to related parties and exercise of common stock options, net of transaction costs			$ 1,030								$ 1,030
Compensation expense related to stock options for services	26,873								26,873
Unrealized gain (loss) on available-for-sale securities	(127)											(127)
Net Loss	(241,846)												(241,846)
Ending balance (in shares) at Dec. 31, 2021				1,969,797		17,103,395
Ending balance at Dec. 31, 2021	196,107			$ 0		$ 2			863,495			(80)	(667,310)
Increase (Decrease) in Stockholders' Equity
Issuance of common and preferred shares in equity offerings, excluding to related parties, net of transaction costs (in shares)					400,000		783,344
Issuance of common shares in equity offering, excluding to related parties, net of transaction costs		255,382								255,382
Sale of common shares to related parties and exercise of common stock options, net of transaction costs ( in shares)								215,784
Sale of common shares to related parties and exercise of common stock options, net of transaction costs			8,955								8,955
Compensation expense related to stock options for services	31,625								31,625
Unrealized gain (loss) on available-for-sale securities	48											48
Hercules warrant	622								622
Net Loss	$ (295,350)												(295,350)
Ending balance (in shares) at Dec. 31, 2022	18,102,523			2,369,797		18,102,523
Ending balance at Dec. 31, 2022	$ 197,389			$ 0		$ 2			1,160,079			(32)	(962,660)
Increase (Decrease) in Stockholders' Equity
Issuance of common and preferred shares in equity offerings, excluding to related parties, net of transaction costs (in shares)							1,346,199	426,705
Issuance of common shares in equity offering, excluding to related parties, net of transaction costs		$ 260,187	$ 270,292							$ 260,187	$ 270,292
Sale of common shares to related parties and exercise of common stock options, net of transaction costs ( in shares)	460,385
Compensation expense related to stock options for services	$ 49,735								49,735
Unrealized gain (loss) on available-for-sale securities	500											500
Hercules warrant	860								860
Net Loss	$ (373,630)												(373,630)
Ending balance (in shares) at Dec. 31, 2023	19,875,427			2,369,797		19,875,427
Ending balance at Dec. 31, 2023	$ 405,333			$ 0		$ 2			$ 1,741,153			$ 468	$ (1,336,290)