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Quarterly Financial Data (unaudited) (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2023
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Revenues:                      
Total revenues $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0
Operating expenses:                      
Research and development 70,640,000 70,951,000 68,605,000 62,154,000 70,742,000 68,271,000 58,499,000 47,929,000 272,350,000 245,441,000 205,164,000
General and administrative 46,536,000 27,583,000 17,845,000 16,182,000 14,557,000 12,141,000 11,774,000 9,658,000 108,146,000 48,130,000 37,318,000
Total operating expenses 117,176,000 98,534,000 86,450,000 78,336,000 85,299,000 80,412,000 70,273,000 57,587,000 380,496,000 293,571,000 242,482,000
Loss from operations (117,176,000) (98,534,000) (86,450,000) (78,336,000) (85,299,000) (80,412,000) (70,273,000) (57,587,000) (380,496,000) (293,571,000) (242,482,000)
Interest income 8,953,000 3,298,000 3,551,000 3,776,000 1,076,000 717,000 323,000 69,000 19,578,000 2,185,000 363,000
Interest expense (3,971,000) (3,504,000) (2,901,000) (2,336,000) (1,682,000) (1,502,000) (780,000) 0 (12,712,000) (3,964,000) 0
Other income 0 0 0 0 0 0 0 0 0 0 273,000
Net loss $ (112,194,000) $ (98,740,000) $ (85,800,000) $ (76,896,000) $ (85,905,000) $ (81,197,000) $ (70,730,000) $ (57,518,000) $ (373,630,000) $ (295,350,000) $ (241,846,000)
Net loss per common share:                      
Basic net loss per common share (in dollars per share) $ (5.68) $ (5.34) $ (4.69) $ (4.23) $ (4.98) $ (4.75) $ (4.14) $ (3.36) $ (19.99) $ (17.23) $ (14.63)
Diluted net loss per common share (in dollars per share) $ (5.68) $ (5.34) $ (4.69) $ (4.23) $ (4.98) $ (4.75) $ (4.14) $ (3.36) $ (19.99) $ (17.23) $ (14.63)
Basic weighted average number of common shares outstanding (in shares) 19,760,842 18,476,414 18,310,952 18,187,924 17,237,517 17,103,395 17,103,395 17,103,395 18,687,774 17,137,201 16,535,188
Diluted weighted average number of common shares outstanding (in shares) 19,760,842 18,476,414 18,310,952 18,187,924 17,237,517 17,103,395 17,103,395 17,103,395 18,687,774 17,137,201 16,535,188