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Commitments and Contingencies (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2023
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Commitments and Contingencies                        
Revenues $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0  
Obtaining a right-of-use asset in exchange for a lease liability                 $ 1,628,000 $ 583,000 $ 376,000  
Research, Development and Commercialization Agreement | Hoffmann-La Roche ("Roche")                        
Commitments and Contingencies                        
Remainder of future milestone payments                       $ 8,000,000