Stock-based Compensation - Narrative (Details) - USD ($) $ / shares in Units, $ in Millions	1 Months Ended	12 Months Ended
	Sep. 30, 2023	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Unrecognized stock-based compensation expense
Stock options, restricted stock and performance stock units convertible, shares issuable (in shares)		2,881,896
Options granted (in shares)		31,111
Inducement Plan 2023
Unrecognized stock-based compensation expense
Shares available for future issuance (in shares)		193,392
Common stock reserved for future issuance (in shares)	500,000
Maximum | Stock Plan 2015
Unrecognized stock-based compensation expense
Expiration period		10 years
Maximum | Inducement Plan 2023
Unrecognized stock-based compensation expense
Expiration period	10 years
Common stock options
Unrecognized stock-based compensation expense
Proceeds resulting from exercise of stock options		$ 34.0	$ 9.0	$ 1.0
Total intrinsic value of options exercised		$ 70.4	$ 47.3	$ 0.1
Weighted-average grant date fair value of options (in dollars per share)		$ 149.15	$ 54.68	$ 73.29
Unrecognized stock compensation expense		$ 118.2
Weighted average remaining period (in years)		2 years 7 months 28 days
Common stock options | Stock Plan 2015
Unrecognized stock-based compensation expense
Shares available for future issuance (in shares)		711,054
Performance-based restricted stock units
Unrecognized stock-based compensation expense
Equity instruments other than options, outstanding (in shares)		150,000
Equity instruments other than options, weighted average grant date fair value (in dollars per share)		$ 146.37
Options granted (in shares)		50,000