Stockholders' Equity - At The Market Issuances (Details) - USD ($)		1 Months Ended			3 Months Ended	12 Months Ended				24 Months Ended
	Sep. 28, 2023	May 31, 2023	Dec. 31, 2022	Nov. 30, 2020	Dec. 31, 2023	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2022
Public Stock Offering
Stockholders' Equity (Deficit)
Sale of stock, number of shares issued in transaction (in shares)	1,248,098		738,900		0	98,101	738,900	497,043		1,235,943
Proceeds from issuance of common stock, gross	$ 500,000,000		$ 159,100,000			$ 25,200,000				$ 199,900,000
Proceeds from issuance of common stock, net			$ 155,900,000			24,500,000				$ 195,800,000
Common stock reserved for future issuance amount					$ 174,800,000	$ 174,800,000
2020 Sales Agreement
Stockholders' Equity (Deficit)
Sale of stock, number of shares issued in transaction (in shares)						1,126,733		1,087,126	39,607
Proceeds from issuance of common stock, gross						$ 137,400,000
Proceeds from issuance of common stock, net						134,800,000
2021 Sales Agreement
Stockholders' Equity (Deficit)
Common stock reserved for future issuance amount					$ 0	0
Cowen & Co. LLC | Maximum | 2020 Sales Agreement
Stockholders' Equity (Deficit)
Maximum aggregate offering price				$ 200,000,000
Cowen & Co. LLC | Maximum | 2021 Sales Agreement
Stockholders' Equity (Deficit)
Maximum aggregate offering price						$ 200,000,000
Cowen & Co. LLC | Maximum | 2023 Sales Agreement Amendment
Stockholders' Equity (Deficit)
Maximum aggregate offering price		$ 200,000,000