Condensed Consolidated Statements Of Stockholders' Equity - USD ($) $ in Thousands	Total	Preferred Stock	Common stock	Additional paid-in Capital	Accumulated other comprehensive income (loss)	Accumulated deficit
Balance at Dec. 31, 2021	$ 196,107		$ 2	$ 863,495	$ (80)	$ (667,310)
Balance (in shares) at Dec. 31, 2021		1,969,797	17,103,395
Increase (Decrease) in Stockholders' Equity
Compensation expense related to stock options for services	7,477			7,477
Unrealized loss on marketable securities	(322)				(322)
Net loss	(57,518)					(57,518)
Balance at Mar. 31, 2022	145,744		$ 2	870,972	(402)	(724,828)
Balance (in shares) at Mar. 31, 2022		1,969,797	17,103,395
Balance at Dec. 31, 2022	$ 197,389		$ 2	1,160,079	(32)	(962,660)
Balance (in shares) at Dec. 31, 2022	18,102,523	2,369,797	18,102,523
Increase (Decrease) in Stockholders' Equity
Sale of common shares to related parties and exercise of common stock options, net of transaction cost	$ 17,903			17,903
Sale of common shares to related parties and exercise of common stock options, net of transaction cost ( in shares)			180,551
Compensation expense related to stock options for services	11,250			11,250
Unrealized loss on marketable securities	(54)				(54)
Hercules warrant	544			544
Net loss	(76,896)					(76,896)
Balance at Mar. 31, 2023	$ 150,136		$ 2	$ 1,189,776	$ (86)	$ (1,039,556)
Balance (in shares) at Mar. 31, 2023	18,283,074	2,369,797	18,283,074