Stock-based Compensation - Expense (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Stock-based compensation expense
Stock-based compensation expense	$ 11,250	$ 7,477
Research and development
Stock-based compensation expense
Stock-based compensation expense	5,385	3,187
General and administrative
Stock-based compensation expense
Stock-based compensation expense	5,865	4,290
Stock options
Stock-based compensation expense
Stock-based compensation expense	8,598	7,477
Restricted Stock Units (RSUs)
Stock-based compensation expense
Stock-based compensation expense	$ 2,652	$ 0