Liquidity and Uncertainties (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended						9 Months Ended
	May 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Net loss		$ (81,197)	$ (70,730)	$ (57,518)	$ (63,100)	$ (61,651)	$ (52,546)	$ (209,445)	$ (177,297)
Accumulated deficit		(876,755)						(876,755)		$ (667,310)
Debt instrument, Face amount		50,000						50,000
Cash, cash equivalents and marketable securities		$ 153,200						$ 153,200
Term Loan [Member]
Debt instrument, Face amount	$ 250,000
Proceeds from issuance of debt	$ 50,000