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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Cash flows from operating activities:    
Net loss $ (85,158) $ (34,779)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 10,535 13,777
Depreciation and amortization expense 240 56
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,072) (906)
Accounts payable 3,826 (2,041)
Accrued expense 16,311 5,607
Accrued interest, net of interest received on maturity of investments 554 268
Net cash used in operating activities (54,764) (18,018)
Cash flows from investing activities:    
Purchases of marketable securities (153,869) (266,116)
Sales and maturities of marketable securities 224,015 299,103
Purchases of property and equipment, net of disposals (321) (40)
Net cash provided by investing activities 69,825 32,947
Cash flows from financing activities:    
Proceeds from the sale of related party stock and exercise of common stock options, net of transaction costs 109 200
Net cash provided by financing activities 109 200
Net increase in cash and cash equivalents 15,170 15,129
Cash and cash equivalents at beginning of period 46,697 57,379
Cash and cash equivalents at end of period 61,867 72,508
Supplemental disclosure of cash flow information:    
Obtaining a right-of-use asset in exchange for a lease liability $ 0 $ 900