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License and Development Agreements (Details) (Roche Agreement, Roche, USD $)
In Millions, unless otherwise specified
1 Months Ended 3 Months Ended 9 Months Ended 24 Months Ended
Jan. 31, 2009
Sep. 30, 2012
Dec. 31, 2011
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2010
Roche Agreement | Roche
             
License and Development Agreements              
Upfront license fee received $ 16            
Initial term for research 2 years            
Amount received related to research and development support             21.2
Accelerated recognition of remaining deferred revenue from upfront payment     2.1        
License revenue recognized   $ 0   $ 1.1 $ 0 $ 3.4