<SEC-DOCUMENT>0001047469-17-004772-index.html : 20170726
<SEC-HEADER>0001047469-17-004772.hdr.sgml : 20170726
<ACCEPTANCE-DATETIME>20170726122404
ACCESSION NUMBER:		0001047469-17-004772
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20170726
DATE AS OF CHANGE:		20170726

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MADRIGAL PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001157601
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-219304
		FILM NUMBER:		17982111

	BUSINESS ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE, SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428
		BUSINESS PHONE:		404-380-9263

	MAIL ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE, SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SYNTA PHARMACEUTICALS CORP
		DATE OF NAME CHANGE:	20010815
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>a2232779z424b3.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: a2232779z424b3.htm

</DOCUMENT>
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<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g467069.jpg
<DESCRIPTION>G467069.JPG
<TEXT>
Document 2 - file: g467069.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g81786.jpg
<DESCRIPTION>G81786.JPG
<TEXT>
Document 3 - file: g81786.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g809717.jpg
<DESCRIPTION>G809717.JPG
<TEXT>
Document 4 - file: g809717.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>g823383.jpg
<DESCRIPTION>G823383.JPG
<TEXT>
Document 5 - file: g823383.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g777688.jpg
<DESCRIPTION>G777688.JPG
<TEXT>
Document 6 - file: g777688.jpg

</DOCUMENT>
</SEC-DOCUMENT>