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Property and Equipment
12 Months Ended
Dec. 31, 2011
Property and Equipment  
Property and Equipment

(4) Property and Equipment

        Property and equipment consist of the following at December 31:

 
  2011   2010  
 
  (in thousands)
 

Laboratory equipment

  $ 12,468   $ 12,387  

Leasehold improvements

    4,847     4,528  

Computers and software

    2,315     2,177  

Furniture and fixtures

    1,135     1,050  
           

 

    20,765     20,142  

Less accumulated depreciation and amortization

    (19,358 )   (17,961 )
           

 

  $ 1,407   $ 2,181  
           

        Depreciation and amortization expenses of property and equipment, including equipment purchased under capital leases, were approximately $1.5 million, $1.9 million and $2.5 million for the years ended December 31, 2011, 2010 and 2009, respectively.

        The net book value and accumulated amortization of equipment under capital lease was approximately $16,000 and $43,000, respectively, at December 31, 2011, and $0.4 million and $0.9 million, respectively, at December 31, 2010.