X0306 4 2020-08-17 0 0001157601 MADRIGAL PHARMACEUTICALS, INC. MDGL 0001288452 BAY CITY CAPITAL LLC 750 BATTERY STREET, SUITE 400 SAN FRANCISCO CA 94111 0 0 1 0 0001359070 Bay City Capital Management IV LLC 750 BATTERY STREET, SUITE 400 SAN FRANCISCO CA 94111 0 0 1 0 0001360243 Bay City Capital Fund IV, L.P. 750 BATTERY STREET, SUITE 400 SAN FRANCISCO CA 94111 0 0 1 0 0001333817 BAY CITY CAPITAL FUND IV CO INVESMENT FUND LP 750 BATTERY STREET, SUITE 400 SAN FRANCISCO CA 94111 0 0 1 0 Common Stock 2020-08-17 4 S 0 12500 110.73 D 60375 D Common Stock 2020-08-18 4 S 0 10197 110.03 D 50178 D Common Stock 2020-08-19 4 S 0 7303 107.64 D 42875 D Common Stock 3729141 I See Footnotes Common Stock 81380 I See Footnotes Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. The securities are held by Fund IV. The securities are held by Co-Investment IV. Bay City Capital LLC, a Delaware limited liability company, By: /s/ Fred Craves, Managing Director 2020-08-19 Bay City Capital Management IV LLC, a Delaware limited liability company, by Bay City Capital LLC, its Manager, By: /s/ Fred Craves, Managing Director 2020-08-19 Bay City Capital Fund IV, L.P., a Delaware limited partnership, by Bay City Capital Management IV LLC, its General Partner, by Bay City Capital LLC, its Manager, By: /s/ Fred Craves, Managing Director 2020-08-19 Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership, by Bay City Capital Management IV LLC, its General Partner, by Bay City Capital LLC, its Manager, By: /s/ Fred Craves, Managing Director 2020-08-19