X0305 4 2012-05-22 0 0001145404 CORNERSTONE THERAPEUTICS INC CRTX 0001296114 Harper James A 1255 CRESCENT GREEN DRIVE SUITE 250 CARY NC 27518 1 0 0 0 Option to Purchase Common Stock (Right to Buy) 5.11 2012-05-22 4 A 0 15000 0.00 A 2022-05-22 Common Stock 15000 15000 D Shares subject to these options vest in 12 approximately equal monthly installments with the first installment vesting as of June 22, 2012. These options were granted pursuant to the terms of Cornerstone Therapeutics Inc. Amended and Restated Non-Employee Director Compensation and Reimbursement Policy, effective May 18, 2011. /s/ Andrew K.W. Powell, attorney in fact for James Harper pursuant to a power of attorney 2012-05-23