X0202 4 2007-12-27 0 0001145404 CRITICAL THERAPEUTICS INC CRTX 0001303192 Townsend Scott B C/O CRITICAL THERAPEUTICS, INC. 60 WESTVIEW STREET LEXINGTON MA 02421 0 1 0 0 GENERAL COUNSEL and SVP LEGAL Common Stock 2007-12-27 4 F 0 4270 1.28 D 59868 D Pursuant to a tax withholding right approved by the Company's board of directors, the reporting person satisfied his tax withholding obligations upon the vesting of restricted stock granted to him on December 27, 2006 through a deemed disposition to the Company of a portion of the restricted shares scheduled to vest on December 27, 2007. The Company deducted and retained these shares from the number of restricted shares scheduled to vest. /s/ Scott B. Townsend 2007-12-28