X0202 4 2005-11-02 0 0001145404 CRITICAL THERAPEUTICS INC CRTX 0001242616 THOMAS FRANK E C/O CRITICAL THERAPEUTICS, INC. 60 WESTVIEW ROAD LEXINGTON MA 02421 0 1 0 0 CFO, SVP Finance and Treasurer Common Stock 2005-11-02 4 M 0 1000 5.63 A 14000 D Option to Purchase Common Stock 5.63 2005-11-02 4 M 0 1000 D 2014-04-25 Common Stock 1000 199333 D Of the option to purchase 213,333 of Common Stock of Critical Therapeutics, Inc. originally granted on April 26, 2004, 32,000 of the underlying shares were vested as of April 26, 2004. 45,333 of the underlying shares became exercisable on April 26, 2005 and the remaining 136,000 of the underlying shares become exercisable in 36 equal monthly installments beginning one month thereafter. Not applicable. /s/ Frank E. Thomas 2005-11-02