X0306 4 2018-02-22 0001145197 INSULET CORP PODD 0001665678 Alpuche Charles C/O INSULET CORPORATION 600 TECHNOLOGY PARK DRIVE, SUITE 200 BILLERICA MA 01821 1 EVP & Chief Operations Officer Common Stock 2018-02-22 4 F 0 1062 80.46 D 52515 D This transaction represents the withholding of shares received upon the vesting of restricted stock units to cover the associated tax obligations. Includes 5,341 restricted stock units granted on February 3, 2016, which vest on February 3, 2019; 13,670 performance share units granted on February 24, 2016, which vest one-half of the total units on February 24, 2018 and one-half of the total units on February 24, 2019; 7,212 restricted stock units granted on February 22, 2017, which vest one-half of the total units on February 22, 2019 and one-half of the total units on February 22, 2020; and 6,711 restricted stock units granted on February 14, 2018, which vest one-third of the total units on February 14, 2019, one-third of the total units on February 14, 2020 and one-third of the total units on February 14, 2021, subject to continued employment. Vested shares will be delivered to the reporting person as soon as practicable following a vesting date. Includes an aggregate of 729 shares acquired under the Insulet Corporation 2007 Employee Stock Purchase Plan on the following dates: 613 shares acquired on May 31, 2017 and 116 shares acquired on November 30, 2017. /s/ David Colleran, attorney-in-fact 2018-02-26