X0203 0001143313 NYSE Amex 0000802724 INSITE VISION INC 001-14207

965 Atlantic Avenue Alameda CA CALIFORNIA 94501

510-865-8800 Common Stock, $0.01 Par Value 17 CFR 240.12d2-2(b) Janice O'Neill Senior Vice President - Corporate Compliance 2009-06-10