X0203 0001143313 AMERICAN STOCK EXCHANGE LLC 0000097745 THERMO FISHER SCIENTIFIC INC. 001-8002

81 Wyman Street P.O. Box 9046 Waltham MA MASSACHUSETTS 02454-9046

(781) 622-1000 3 1/4% Convertible Subordinated Debentures, expiring November 1, 2007 17 CFR 240.12d2-2(a)(2) Kerri L. Ramirez Manager, Corporate Actions and Proxy Rulings 2007-01-08