Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 246,091	$ 856,869
Short-term marketable securities		173,145
Accounts receivable, net of allowances of $21,064 and $20,631, respectively	214,398	207,071
Inventory, net	315,845	300,623
Prepaid income taxes	5,425	4,727
Prepaid expenses and other current assets	20,665	19,749
Total current assets	802,424	1,562,184
Property and equipment, net	303,664	286,369
Intangible assets, net	242,675	152,264
Goodwill	633,467	559,553
Operating lease right-of-use assets	102,987	102,270
Deferred tax assets	48,003	15,755
Restricted cash and investments	1,494	1,494
Other assets	19,361	13,193
Total assets	2,154,075	2,693,082
Current liabilities:
Accounts payable and accrued liabilities	115,614	110,401
Contingent consideration liabilities	7,986	7,289
Accrued payroll and related expenses	66,596	63,421
Operating lease liabilities	9,867	7,875
Income tax liabilities	828	2,073
Senior convertible notes		645,303
Total current liabilities	200,891	836,362
Long-term senior convertible notes	884,984	766,226
Deferred tax liabilities	3,049	2,807
Operating lease liabilities	111,592	111,634
Contingent consideration liabilities	139,824	29,752
Other long-term liabilities	18,528	22,686
Commitments and contingencies
Redeemable equity component of senior convertible notes		4,697
Stockholders’ equity:
Preferred stock, $0.001 par value; 5,000 shares authorized, none outstanding
Common stock, $0.001 par value; 150,000 shares authorized at December 31, 2021 and December 31, 2020; 58,469 shares issued and 51,769 outstanding at December 31, 2021; 57,945 shares issued and 51,376 outstanding at December 31, 2020	63	62
Additional paid-in capital	1,434,976	1,550,001
Accumulated other comprehensive loss	(7,792)	(7,585)
Retained earnings	45,708	45,322
Treasury stock at cost; 6,700 shares and 6,569 shares at December 31, 2021 and December 31, 2020, respectively	(677,748)	(668,882)
Total equity	795,207	918,918
Total liabilities and equity	$ 2,154,075	$ 2,693,082