Balance Sheet Details (Tables)

12 Months Ended

Dec. 31, 2016

Balance Sheet Details [Abstract]

Property and Equipment Net

Property and Equipment, net

Property and equipment, net, consisted of the following (in thousands, except years):

		December 31,
	Useful Life	2016			2015
Instrument sets	4	$	249,592		$	214,893
Machinery and equipment	5 to 7		37,837			26,871
Computer equipment and software	3 to 7		71,258			55,480
Leasehold improvements	2 to 15		21,278			17,331
Furniture and fixtures	3 to 7		7,625			5,884
Building and improvements	10 to 20		16,558			10,875
Land	—		541			1,288
			404,689			332,622
Less: accumulated depreciation and amortization			(223,165	)		(191,181	)
		$	181,524		$	141,441

Goodwill and Intangible Assets

Goodwill and Intangible Assets

Goodwill and intangible assets as of December 31, 2016 consisted of the following (in thousands, except years):

	Weighted-
	Average
	Amortization
	Period	Gross		Accumulated			Intangible
	(in years)	Amount		Amortization			Assets, net
Intangible Assets Subject to Amortization:
Developed technology	8	$	247,148	$	(66,833	)	$	180,315
Manufacturing know-how and trade secrets	13		20,572		(13,604	)		6,968
Trade name and trademarks	9		25,200		(7,478	)		17,722
Customer relationships	9		117,018		(30,880	)		86,138
Total intangible assets subject to amortization	9	$	409,938	$	(118,795	)	$	291,143
Intangible Assets Not Subject to Amortization:
Goodwill								485,685
Total goodwill and intangible assets, net							$	776,828

Goodwill and intangible assets as of December 31, 2015 consisted of the following (in thousands, except years):

	Weighted-
	Average
	Amortization
	Period	Gross		Accumulated			Intangible
	(in years)	Amount		Amortization			Assets, net
Intangible Assets Subject to Amortization:
Developed technology	9	$	92,648	$	(37,382	)	$	55,266
Manufacturing know-how and trade secrets	12		21,787		(13,296	)		8,491
Trade name and trademarks	11		9,500		(5,068	)		4,432
Customer relationships	8		44,752		(27,865	)		16,887
Total intangible assets subject to amortization	10	$	168,687	$	(83,611	)	$	85,076
Intangible Assets Not Subject to Amortization:
Goodwill								154,281
Total goodwill and intangible assets, net							$	239,357

Changes to Goodwill

The changes to goodwill are comprised of the following (in thousands):

(in thousands)
December 31, 2015
Gross goodwill	$	162,581
Accumulated impairment loss		(8,300	)
		154,281
Changes to gross goodwill
Increases recorded in business combinations		330,488
Changes resulting from foreign currency fluctuations		916
		331,404
December 31, 2016
Gross goodwill		493,985
Accumulated impairment loss		(8,300	)
	$	485,685

Future Amortization Expense Related to Intangible Assets

Total future amortization expense related to intangible assets subject to amortization at December 31, 2016 is set forth in the table below (in thousands):

2017	$	48,751
2018		46,658
2019		44,973
2020		44,517
2021		42,598
Thereafter through 2026		63,646
Total future amortization expense	$	291,143

Accounts Payable and Accrued Liabilities

Accounts Payable and Accrued Liabilities

Accounts payable and accrued liabilities consisted of the following (in thousands):

	December 31,
	2016		2015
Accrued expenses	$	42,355	$	31,187
Accounts payable		9,121		6,792
Distributor commissions payable		8,836		8,502
Other taxes payable		7,789		6,386
Royalties payable		4,877		4,454
Others		4,607		3,665
Accounts payable and accrued liabilities	$	77,585	$	60,986