<?xml version="1.0"?>
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    <periodOfReport>2021-01-15</periodOfReport>

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    <issuer>
        <issuerCik>0001142417</issuerCik>
        <issuerName>NEXSTAR MEDIA GROUP, INC.</issuerName>
        <issuerTradingSymbol>NXST</issuerTradingSymbol>
    </issuer>

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            <rptOwnerName>SOOK PERRY A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEXSTAR MEDIA GROUP, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>545 E. JOHN CARPENTER FREEWAY, SUITE 700</rptOwnerStreet2>
            <rptOwnerCity>IRVING</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>75062</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
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            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Executive Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

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    <derivativeTable>
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            <transactionDate>
                <value>2021-01-15</value>
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                <value></value>
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                <transactionShares>
                    <value>15625</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
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                <transactionAcquiredDisposedCode>
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            <exerciseDate>
                <footnoteId id="F2"/>
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            <expirationDate>
                <footnoteId id="F2"/>
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                <underlyingSecurityTitle>
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                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>15625</value>
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                <footnoteId id="F4"/>
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                <underlyingSecurityTitle>
                    <value>Class A Common Stock</value>
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                </sharesOwnedFollowingTransaction>
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    <footnotes>
        <footnote id="F1">As restricted stock units (&quot;RSUs&quot;) vest, they are converted into shares of Class A Common Stock on a one-for-one basis at the vesting date.</footnote>
        <footnote id="F2">62,500 RSUs were awarded on January 15, 2019, of which 15,625 RSUs equally over four years at each anniversary of the award through January 15, 2023.</footnote>
        <footnote id="F3">62,500 RSUs were awarded on January 15, 2020, of which 20,833 RSUs vest equally over three years at each anniversary of the award through January 15, 2023.</footnote>
        <footnote id="F4">83,334 performance-based RSUs were awarded on January 15, 2019 and will vest in full on January 15, 2021, subject to the achievement of pre-established company performance metrics. The Compensation Committee of Nexstar's Board of Directors performed an assessment and determined that the conditions were satisfied, thus, the 83,334 performance-based RSUs vested in full on January 15, 2021.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Mark Hoyla, Attorney-in-Fact for Perry A. Sook</signatureName>
        <signatureDate>2021-01-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
