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Note 15 - Related Party Transactions (Details Textual) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Mar. 10, 2016
Chairman of Eontec [Member] | Minimum [Member]      
Beneficial Ownership Percentage 5.00%    
Eontec [Member] | License Agreement [Member]      
Related Party Transaction, Amounts of Transaction $ 0 $ 5,000  
The 2016 Purchase Agreement [Member]      
Common Stock Purchase Agreement, Number of Shares Authorized to Issue and Sell to Investors     405,000,000
Common Stock Purchase Agreement, Value of Shares Authorized to Issue and Sell to Investors     $ 63,400,000