X0201 4 2004-02-19 1 0001034842 RIGEL PHARMACEUTICALS INC RIGL 0001140366 FRAZIER HEALTHCARE IV LP 601 UNION STREET, SUITE 3200 SEATTLE WA 98101 0 0 1 0 0001281153 FHM IV LP TWO UNION SQUARE 601 UNION STREET STE 3200 SEATTLE WA 98101 0 0 1 0 0001281154 FHM IV LLC TWO UNION SQUARE 601 UNION STREET STE 3200 SEATTLE WA 98101 0 0 1 0 Common Stock 2004-02-19 4 S 0 78040 18.8 D 1217467 D Common Stock 2004-02-19 4 S 0 396 18.8 D 6180 I See Footnote This number assumes that 10,221 shares currently held by Frazier Healthcare IV, L.P. and 52 shares currently held by Frazier Affiliates IV, L.P., which may be sold by Frazier Healthcare IV, L.P. and Frazier Affiliates IV, L.P. to the Underwriters at the option of the Underwriters as part of an overallotment option, were sold as of February 19, 2004. The Underwriting Agreement, dated February 19, 2004, by and between the Issuer, the Selling Stockholders (as defined therein) and Underwriters(as defined therein), has previously been filed as Exhibit 1.1 to the Form 8-K of the Issuer filed February 20, 2004. Upon the conclusion of the transactions as set forth in the Prospectus of the Issuer filed pursuant to Rule 424(b)(5) (Registration Nos. 333-111777 and 333-106942) on February 20, 2004, Frazier Healthcare IV, L.P. will hold less than 10% of the outstanding common stock of the Issuer. Represents 6,180 shares held of record by Frazier Affiliates IV, L.P., an entity that invests and divests side-by-side with Frazier Healthcare IV, L.P. Alan D. Frazier, a director of Rigel since October 1997, is one of four managing members of FHM IV, LLC, the general partner of FHM IV, L.P., which is the general partner of both Frazier Healthcare IV, L.P. and Frazier Affiliates IV, L.P. /s/ Alan D. Frazier, the Managing Director of FHM IV, L.L.C., the general partner of FHM IV, L.P., the general partner of Frazier Healthcare IV, L.P. and Frazier Affiliates IV, L.P. 2004-02-24