Property, Plant and Equipment

12 Months Ended

Dec. 31, 2020

Property Plant And Equipment [Abstract]

Property, Plant and Equipment

7. Property, Plant and Equipment

Property, plant and equipment consisted of the following (in millions):

	As of December 31,
	2020			2019
Land	$	27.7		$	27.6
Building and equipment		2,197.8			2,007.0
Capitalized software costs		455.8			482.4
Instruments		3,518.3			3,250.5
Construction in progress		125.3			149.3
		6,324.9			5,916.8
Accumulated depreciation		(4,277.2	)		(3,839.4	)
Property, plant and equipment, net	$	2,047.7		$	2,077.4

Depreciation expense was $435.1 million, $421.8 million and $442.6 million for the years ended December 31, 2020, 2019 and 2018, respectively.

We had $24.4 million and $39.8 million of property, plant and equipment included in accounts payable as of December 31, 2020 and 2019, respectively.