September 30,

December 31,

2025

2024

(in millions)

Land

$

22.5

$

18.5

Buildings and equipment

2,420.9

2,273.1

Capitalized software costs

612.1

575.1

Instruments

3,894.0

3,589.6

Construction in progress

272.7

233.9

7,222.2

6,690.2

Accumulated depreciation

(5,027.9

)

(4,641.4

)

Property, plant and equipment, net

$

2,194.3

$

2,048.8