Property, Plant and Equipment

12 Months Ended

Dec. 31, 2015

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

7. Property, Plant and Equipment

Property, plant and equipment consisted of the following (in millions):

As of December 31,	2015			2014
Land	$	39.6		$	20.4
Building and equipment		1,789.3			1,283.4
Capitalized software costs		330.1			294.7
Instruments		2,160.5			1,692.8
Construction in progress		108.4			115.8
		4,427.9			3,407.1
Accumulated depreciation		(2,365.3	)		(2,121.8	)
Property, plant and equipment, net	$	2,062.6		$	1,285.3

Depreciation expense was $375.0 million, $268.6 million and $262.6 million for the years ended December 31, 2015, 2014 and 2013, respectively.