June 30,

December 31,

2025

2024

(in millions)

Land

$

22.6

$

18.5

Buildings and equipment

2,411.2

2,273.1

Capitalized software costs

606.1

575.1

Instruments

3,834.0

3,589.6

Construction in progress

271.6

233.9

7,145.5

6,690.2

Accumulated depreciation

(4,969.8

)

(4,641.4

)

Property, plant and equipment, net

$

2,175.7

$

2,048.8