X0306 4 2017-02-24 0 0001068851 PROSPERITY BANCSHARES INC PB 0001136856 HOLMES NED S 55 WAUGH DRIVE, SUITE 1111 HOUSTON TX 77027 1 0 0 0 Common Stock 2017-02-24 5 G 0 E 5000 0.00 D 157205 D Common Stock 2017-04-18 4 A 0 1000 0.00 A 158205 D Common Stock 2000 I By spouse Common Stock 113125 I By profit sharing plan Common Stock 8820 I As trustee of granchildren's trust Common Stock 48500 I As trustee of SSH trust for adult daughter Common Stock 27500 I As trustee of SSH trust for adult daughter Common Stock 3720 I By trust Common Stock 70070 I By limited partnership Includes 2,118 shares acquired through the Prosperity Bancshares, Inc. dividend reinvestment plan since the last filing by the reporting person. /s/ Ned S. Holmes 2017-04-19