X0306 4 2021-07-21 0 0001757898 STERIS plc STE 0001136554 LEWIS DAVID B C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN L2 2 IRELAND 1 0 0 0 Ordinary Shares 2021-07-21 4 A 0 1561 31.61 A 8245 D Employee Stock Option (right to buy) 31.61 2021-07-21 4 M 0 1561 0.00 A 2021-08-03 Ordinary Shares 1561 0 D This option is part of an option to purchase 3,121 STERIS ordinary shares, which are fully vested, which was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 3,121 Old STERIS ordinary shares for $31.61 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2021-07-22