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Stock-Based Compensation (Tables)
 3 Months Ended
Mar. 31, 2022
Share-based Payment Arrangement [Abstract]  
Schedule of assumptions used in the Black-Scholes option-pricing model
The assumptions used in the Black-Scholes option-pricing model were as follows:

Three Months Ended
March 31, 2022
Volatility
 100.0%
Risk-free interest rate
1.04%
Expected life (in years)
 2.81
Dividend yield0 %
Summary of stock option activity for employees and directors
A summary of stock option activity for employees, directors and consultants is as follows:
Number of Shares
Weighted Average
Exercise Price
Outstanding as of December 31, 20213,618,145 $13.55 
Granted332,296 8.72 
Forfeited(444,972)16.28 
Outstanding as of March 31, 20223,505,469 12.74 
Options vested and exercisable as of March 31, 20221,089,599 $14.19 
Schedule of restricted stock units activity The following table summarizes our RSU award activity issued under the 2017 Plan:
Restricted Stock UnitsWeighted-
Average
Grant Date Fair Value
Non-vested at December 31, 2021111,874 $33.27 
Forfeited(13,000)28.60 
Vested and distributed(1,875)51.98 
Non-vested at March 31, 2022
96,999 33.53 
Summary of warrants activity for non-employees A summary of warrants activity was as follows:
Number of Warrants
Weighted Average
Exercise Price
Outstanding as of December 31, 202135,832 $16.75 
Granted131,664 0.01 
Outstanding as of March 31, 2022167,496 3.59 
Warrants exercisable as of March 31, 2022167,496 3.59 
Schedule of performance based and market based issuances The following table summarizes the Company’s outstanding awards under this structure:
Grant DatePerformance MeasuresVesting TermPerformance Period# of SharesExercise Price
December 2017
Weighted Average Price of our common stock is $15.00 for at least twenty trading days within a period of thirty consecutive trading days ending on the trading day prior to January 1, 2023.
Fully vest on January 1, 2023January 1, 2023642,307 $7.50 
August 2018
Weighted Average Price of our common stock is $15.00 for at least twenty trading days within a period of thirty consecutive trading days ending on the trading day prior to January 1, 2023.
Fully vest on January 1, 2023January 1, 2023397,693 $7.50